Treatment

Blood And Marrow Transplant & Cellular Therapy

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A blood and marrow transplant replaces a person's abnormal stem cells with healthy ones from another person (a donor) and is most often used to treat patients with blood cancers or other blood disorders. This procedure allows the recipient to get new stem cells that work properly. We were the first institution to successfully complete a bone marrow transplant– back in 1968.

Overview

A blood and marrow transplant replaces a person's abnormal stem cells with healthy ones from either their own body (autologous transplant) or a donor (allogenic transplant) and is most often used to treat patients with blood cancers or other blood disorders. This procedure allows the recipient to get new stem cells that work properly. 

The three main types of blood and marrow transplant we perform include:

  • Autologous transplant: this is a transplant of cells from the patient’s own body.
  • Allogeneic related donor transplant: this is a transplant of cells from someone related to the patient.
  • Allogeneic unrelated donor transplant: this is a transplant of cells from someone who is not related to the patient.

These transplants are used to treat conditions such as:

  • Blood cancers
  • Lymphoma
  • Leukemia
  • Myelodysplastic syndrome (MDS)
  • Myeloproliferative diseases
  • Multiple myeloma

And more. Our blood and marrow transplant care teams also manage care for patients receiving CAR T-cell therapy, cellular therapies, and some forms of immunotherapy treatment.

In the past, blood and marrow transplant (BMT) treatment options were only available for patients under the age of 60. Recent medical guidance has expanded that age to 79, meaning that many patients who previously would not have been able to receive treatment are now able to get transplant care. Many types of blood cancer and blood disorders are more likely to be diagnosed in older adults, so this shift opens up care options for patients that did not have it before.

Our approach

Our program was the first to successfully complete a bone marrow transplant– back in 1968. Since then, our teams have performed more than 8,000 bone marrow transplants.

People travel from across the country and around the world for Blood and Marrow Transplant (BMT) treatment at our hospitals. University of Minnesota Medical Center and University of Minnesota Masonic Children's Hospital have provided compassionate, expert, innovative care to blood and marrow transplant (BMT) patients for more than 50 years.

Driving Research to Reality

Our BMT Program continues to thrive as one of the most respected BMT research and treatment programs in the world. Here’s why:

  • We offer the highest-quality treatment and care based on your specific circumstances and needs.
  • Our first-rate researchers are committed to turning what they learn through research into successful treatment options.
  • We have the largest umbilical cord blood program in the country, making BMT a realistic option for more patients than ever before.
  • In 2005, our researchers were the first to report the success of using a unique type of donor cells for treatment of an advanced type of leukemia. They used Natural Killer (NK) cells to successfully treat advanced acute myelogenous leukemia (AML).
  • We offer you a patient- and-family-centered care approach to provide high-quality, compassionate care.
  • We continually strive to improve the safety and effectiveness of transplant therapy, to provide you and all our patients with the best possible outcomes.

Information for providers looking to refer patients may be found here.